What is Enteropathy and Intestinal Dysbiosis?
Severe and prolonged enteritis and enteropathy can lead to K-vitamin deficiency and impaired synthesis of factors VII, X, II and IX. In most cases, this deficit does not reach a critical level and remains subclinical, sometimes hemorrhagic syndrome occurs in children under 3 years of age.
Similar disorders are observed with intestinal dysbiosis caused by the ingestion of antibiotics that destroy the normal intestinal microflora; the influence of tetracycline drugs and chloramphenicol is especially unfavorable.
Symptoms of Enteropathy and Intestinal Dysbiosis
In patients, small hemorrhages appear on the skin. In addition to hemorrhages in the skin, there are nasal, gingival and intestinal bleeding. They often precede other bleeding and are so prevailing in the clinical picture that they are mistakenly interpreted as a sign of a local pathological process. The identification of a significant lengthening of prothrombin time brings clarity to this question. Intestinal bleeding can be hidden for a long time, manifested only by increasing anemia of the patient.
Diagnosis of Enteropathy and Intestinal Dysbiosis
Diagnosis is the same as with other forms of K-vitamin deficiency.
Treatment of Enteropathy and Intestinal Dysbiosis
The main treatment method is intravenous or intramuscular administration of vitamin K preparations, the abolition of antibiotics and other antibacterial drugs, the appointment of enzyme and bacterial drugs.
In the most severe cases accompanied by enteropathic hypoproteinemia, plasma transfusion, the introduction of albumin and electrolyte solutions are used.